Figure_7.tif (666.04 kB)
Long-term ISA27 treatment induces cell cycle arrest and a persistent increase in p21 mRNA levels in U87MG cells.
figure
posted on 2013-08-19, 03:55 authored by Barbara Costa, Sara Bendinelli, Pamela Gabelloni, Eleonora Da Pozzo, Simona Daniele, Fabrizio Scatena, Renato Vanacore, Pietro Campiglia, Alessia Bertamino, Isabel Gomez-Monterrey, Daniela Sorriento, Carmine Del Giudice, Guido Iaccarino, Ettore Novellino, Claudia Martini7A) Flow cytometric cell cycle profiling: the figure shows the percentage of untreated and MDM2 inhibitor-treated U87MG cells in G1-, S- and G2/M-phase. 7B) p21 mRNA evaluation: ISA27 treatment resulted in a statistically significant increase in p21 mRNA levels at 24, 48 and 72 h.
