Locoregional cortical saturation (SO₂%) following LPS exposure.

(A) Group averaged SO₂ weighted PAT image for sham controls (NaCl), (B) Group averaged SO₂ weighted PAT image for LPS group, (C) SO₂ Comparison performed between LPS group (N = 11), and NaCl (sham) group (N = 8). SO₂ showed significant decrease in the LPS group compared to NaCl group in left cortex (L) and corpus callosum (cc). The hemisphere contralateral (R) to injection showed no difference. (D) HbT comparison between LPS and NaCl groups, no significant differences were found in any of the explored ROIs. Scale bar: 1 mm; *P<0.05, ***P<0.001.