Location of amino acid changes of EBV proteins encoded by GD1, GD2 and HKNPC1 genomes.

Amino acids changes in EBV proteins with known or putative function due to non-synonymous SNVs are marked by arrows. Red arrows indicate amino acid changes shared by HKNPC1, GD1 and GD2, but not in AG876. Blue arrows indicate amino acid changes shared by HKNPC1 and GD2, but not in GD1 and AG876. Known or predicted cytoplasmic domain (brown), transmembrane domain (green) and extracellular domain (yellow) of membrane proteins are illustrated. Black bars represent specialized features of BALF4 (glycoprotein B), EBNA1, LMP1, EBNA1 and BPLF1.