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Local extrema in the diffusion signal attenuation do not cross-validate well.

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posted on 2015-04-16, 03:31 authored by Ariel Rokem, Jason D. Yeatman, Franco Pestilli, Kendrick N. Kay, Aviv Mezer, Stefan van der Walt, Brian A. Wandell

The two middle columns are independent measurements of the same voxel from the centrum semiovale. The three rows show measurements of this voxel obtained at b = 1000, 2000, and 4000. Notice that local minima and maxima differ between replications (arrows). The DTM (left column) and SFM (right column) predictions generally cross-validate well and are much smoother than the data. This particular voxel was chosen to illustrate a case where there are likely to be crossing fascicles. At this location and at b = 4000, the rRMSE of the DTM is greater than 1, while the rRMSE of the SFM is less than 1.

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