Linear regression analysis of predictors associated with the change score of pruritus intensity.

NOTE. Each participant’s change score of pruritus intensity = follow-up VAS score of pruritus intensity – baseline VAS score of pruritus intensity. Similarly, each participant’s change score of a covariate = follow-up data of a covariate – baseline data of a covariate.

Abbreviations: AST, aspartate transaminase; VAS, visual analog scale.

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Ca×P = Product of albumin-adjusted serum calcium (Ca) and serum phosphorus (P).

1

Model considered only the covariates measured at baseline (gender, Kt/V, use of high-flux dialyzer, pruritus intensity, hematocrit, creatinine, uric acid, fasting glucose, total bilirubin, Ca×P). R2 = 0.736.

2

Model considered both the covariates measured at baseline (Kt/V, pruritus intensity, AST, Ca×P) and the change scores of the covariates (uric acid, fasting glucose, AST). R2 = 0.752.