Figure_5.tif (7.09 MB)
Kidney injury induced by CsA.
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posted on 2014-07-29, 03:13 authored by Carla Patrícia Carlos, Nathália Martins Sonehara, Sonia Maria Oliani, Emmanuel A. BurdmannCollagen fibers stained green by Gomori's method (A–D). Red arrows indicate fibrosis (D). Immunolocalization of tubulointerstitial α-SMA (E–H) and vimentin (I–L) after 7, 14 or 21 days of treatment with vehicle (VH) or 15 mg/kg cyclosporine (CsA). Black arrows indicate renal injury, p≤0.001 (G–H and L). Hematoxylin counterstain. Bars = 10 µm.
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immunologyImmune suppressionphysiologyRenal physiologyGlomerular filtration rateRenal circulationNephrologyRenal failureAcute renal failureChronic kidney diseasemicroalbuminuriaTubulointerstitial diseasepharmacologydrugsImmunosuppressivesAdverse reactionsSurgical and invasive medical proceduresBlood and lymphatic system proceduresBone marrow transplantationtransplantationGraft survivalOrgan transplantationinduced
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