Kidney injury induced by CsA.

<p>Collagen fibers stained green by Gomori's method (A–D). Red arrows indicate fibrosis (D). Immunolocalization of tubulointerstitial α-SMA (E–H) and vimentin (I–L) after 7, 14 or 21 days of treatment with vehicle (VH) or 15 mg/kg cyclosporine (CsA). Black arrows indicate renal injury, p≤0.001 (G–H and L). Hematoxylin counterstain. Bars = 10 µm.</p>