Figure_4.tif (1.73 MB)
Interaction of βig-h3 with integrin α2β1 mediates metastasis of human osteosarcoma cells.
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posted on 2014-03-04, 03:32 authored by Yun-Shan Guo, Rui Zhao, Jie Ma, Wei Cui, Zhen Sun, Bo Gao, Shu He, Yue-Hu Han, Jing Fan, Liu Yang, Juan Tang, Zhuo-Jing LuoThe amounts of cell adhesion (A), invasion (B) and migration (C) were tested in control siRNA or βig-h3 siRNA transfected Saos-2 cells which were incubated with P1E6 and 6S6, alone or combination. Scale = 100 µm. Bars represent the mean of triplicate samples; error bars represent standard deviation. Data are representative of three independent experiments. *P<0.05 by one-way ANOVA analysis.
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BiochemistryBiomacromolecule-ligand interactionsMolecular cell biologyExtracellular matrixintegrinsSignal transductionSignaling pathwayscell adhesiononcologyBasic cancer researchmetastasisCancers and neoplasmsBone and soft tissue sarcomasosteosarcomaCancer risk factorsCancer treatmentpediatricsPublic healthChild healthintegrinmediates
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