Ingenuity pathway analysis of differentially expressed human genes between disease discordant twins.

The analysis compared 789 oligo probes corresponding to 537 human genes significantly differentially expressed (fold change >1.5, q <0.05) between twins discordant for SAID. The upper horizontal axis (blue bars) describe the association of the data set with a given pathway (-log (p value)). The cutoff threshold value (defined as p = 0.05) is shown by the vertical red line. The ratio of the number of genes from the data set that map to a given pathway divided by the total number of molecules that comprise the pathway is shown on the horizontal axis (green triangles). Previously reported viral-related signaling pathways are in bold print.