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Increased demyelination and axonal damage in brain stem.

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posted on 2013-02-21, 04:27 authored by Derek D. C. Ireland, Stephen A. Stohlman, David R. Hinton, Parul Kapil, Robert H. Silverman, Roscoe A. Atkinson, Cornelia C. Bergmann

Brain stems of infected wt and RL−/− mice at day 10 p.i. stained with Luxol Fast Blue (top panels). Scale bar = 100 µm. Immunohistochemical staining for axonal integrity in brain stem at day 10 p.i. (bottom panels) Scale bar = 100 µm. Note more abundant loss of myelin and axonal degeneration in infected RL−/− relative to wt mice.

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