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Immunohistochemical analysis of MAGE-A and MDM4 in a cohort of 225 human primary breast cancer specimens.

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posted on 2015-05-22, 03:43 authored by Lynnette Marcar, Bianca Ihrig, John Hourihan, Susan E. Bray, Philip R. Quinlan, Lee B. Jordan, Alastair M. Thompson, Ted R. Hupp, David W. Meek

aThe P value was achieved using Fisher's exact test

bThe Odds ratio determines the likelihood of elevated MDM4 staining if the tumor is MAGE-A positive as opposed to MAGE-A negative.

Immunohistochemical analysis of MAGE-A and MDM4 in a cohort of 225 human primary breast cancer specimens.

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    E 2 ligase interactionMDM 4 Melanoma antigenE 3 ligase functionMDM 2 partnerubiquitin E 3 ligaseMDM 4 levelsp 53 turnoverMDM 2. StrikinglyRING finger domainMDM 4.p 53 inhibitorMdm 2E 3 ubiquitin ligase activity

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