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Human specific complete HERV-K (HML-2) proviruses within the human genome.

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posted on 2011-05-25, 00:41 authored by Aashish R. Jha, Douglas F. Nixon, Michael G. Rosenberg, Jeffrey N. Martin, Steven G. Deeks, Richard R. Hudson, Keith E. Garrison, Satish K. Pillai

Table 1 Notes

1

The identity and location of human specific complete HERV-K (HML-2) proviruses within the human genome were obtained from previous reports [15], [16]. #HERV-K116, K117, K118 and K119 were previously referred to by their genomic locations.

2

Three HERV-K members have as many differences as the insertionally polymorphic HERV-K113 and four HERV-K members have fewer differences between their LTR than HERV-K113 of which, HERV-K106 and HERV-K116 have identical LTR, however, the latter has a 2846 bp deletion in the pol region.

3

All age estimates are based on inter-LTR comparisons and are in million years (Myr). *Age estimates for HERV-K106 and HERV-K116 are based on 1 SNP between their LTRs. The age of K115 is listed as ‘N/A’ because it cannot be determined by inter-LTR comparison method. The age of K115 was previously estimated to be at least 1.1 Myr using coalescent approach [25].

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