Human specific complete HERV-K (HML-2) proviruses within the human genome.

Table 1 Notes


The identity and location of human specific complete HERV-K (HML-2) proviruses within the human genome were obtained from previous reports [15], [16]. #HERV-K116, K117, K118 and K119 were previously referred to by their genomic locations.


Three HERV-K members have as many differences as the insertionally polymorphic HERV-K113 and four HERV-K members have fewer differences between their LTR than HERV-K113 of which, HERV-K106 and HERV-K116 have identical LTR, however, the latter has a 2846 bp deletion in the pol region.


All age estimates are based on inter-LTR comparisons and are in million years (Myr). *Age estimates for HERV-K106 and HERV-K116 are based on 1 SNP between their LTRs. The age of K115 is listed as ‘N/A’ because it cannot be determined by inter-LTR comparison method. The age of K115 was previously estimated to be at least 1.1 Myr using coalescent approach [25].



CC BY 4.0