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High molecular weight hyaluronan rescue intracellular ∆gnat parasites.

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posted on 2015-09-03, 02:46 authored by Thomas Naderer, Joanne Heng, Eleanor C. Saunders, Joachim Kloehn, Thusitha W. Rupasinghe, Tracey J. Brown, Malcolm J. McConville

RAW 264.7 macrophages were infected with (A) wild type (WT), (B) ∆gnat and (C) ∆gnd promastigotes in the absence of presence of different molecular weight HA. Intracellular parasites numbers at day 1 and 4 post-infection were determined by fluorescence microscopy after staining with Hoechst. Data represents mean and SD from three biological repeats and p-values were determined by the Student’s t-test.

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