Hepatic enzymes and proteins.

Histograms depict serum concentrations of Alanin-Aminotransferase (ALT) (A), aspartat-aminotransferase (AST) (B), albumin (ALB) (C), alkaline phosphatase (ALP) (D), glutamyl transpeptidase (GGT) (E), and serum calcium concentrations (F). Serum IGF-I (G), IGFBP-3 (H), GH (I), iPTH (J), osteocalcin (K), EST (L) were significantly decreased in response to thermal injury and remained diminished for up to three years post-burn. Analysis of serum testosterone (M) and progesterone (N) revealed only moderate increases throughout the first two months post-burn. Bars represent means; error bars correspond to S.E.M. Asterisks denote statistical difference between burned children vs. non-burned children, p<0.05.