Genotype distribution among HAD (cases) and non-HAD (controls) HIV-1-infected patients for all polymorphisms tested.

1<p>Polymorphisms selected from earlier studies that tested for association between genotype and HAD.</p>2<p>In the case of <i>APOE</i> AA, AB and BB refer to no APO E4, one APO E4 allele and two APO E4 alleles, respectively.</p>3<p>SNPs selected from a previous study that found associations between these SNPs and HIV-1 replication in macrophages.</p><p>*Significant difference after correction for multiple testing (n = 12); Bonferroni threshold <i>p</i> = 4.2×10<sup>−3</sup>.</p>