Genomic features with significant differences in their distributions between Alu insert-containing versus insert-free windows.

a

: Testing the hypothesis that Alu insert-containing windows have a right-tailed distribution compared with insert-free windows.

b

: Most conserved elements density as defined in [46].

c

: The frequency of the CCNCCNTNNCCNC motif associated with crossover events at recombination hotspots. They cluster at non-allelic homologous recombination (NAHR) breakpoints and mitochondrial deletion hot spots [50].