Genipin reduces UCP2 expression induced by high glucose in podocytes.

<p>(a) Western blot analysis shows the results of UCP2 in podocytes incubated with D-Glucose for different time periods as indicated. The membrane was reprobed with actin to confirm equal loading of each lane. (b) Graphic presentation of relative UCP2 abundance normalized to actin. *<i>P</i><0.05 vs. control. <i>n</i> = 3. (c) Western blot analysis shows that pre-incubation with genipin inhibited glucose-induced UCP2 expression. The membrane was reprobed with actin to confirm equal loading of each lane. (d) Graphic presentation of relative UCP2 abundance normalized to actin. *<i>P</i><0.05 vs. control. #<i>P</i><0.05 vs. glucose incubated cells without genipin pre-treatment. <i>n</i> = 3.</p>