Fig_3.tif (571.81 kB)
Genetic variants of REN and their gene expressions in renal tissue.
figure
posted on 2015-09-14, 02:47 authored by Yasukazu Makino, Tadashi Konoshita, Atsuhito Omori, Nobuhiro Maegawa, Takahiro Nakaya, Mai Ichikawa, Katsushi Yamamoto, Shigeyuki Wakahara, Tamotsu Ishizuka, Tamehito Onoe, Hiroyuki NakamuramRNA for REN from human renal tissue was measured and compared among genotypes of C-5312T at the distal enhancer site. The values for genetic expression are expressed as logarithmically transformed values of their relative ratio to GAPDH (10−3). Columns and bars show the means and standard errors. The values were as follow (means ± SE): CC, 0.016 ± 0.005; CT, 0.047 ± 0.021 (p = 0.41 vs. CC); TT, 0.198 ± 0.194 (p = 0.011 vs. CC, p < 0.031 vs. CT) (A). The results of the comparisons between genotypes were as follows: CC and CT/TT (0.067 ± 0.031), p = 0.177 (B); CC/CT (0.033 ± 0.012) and TT, p = 0.015 (C).
