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Genes identified as responsible for the action of the first stimulation.

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posted on 2010-02-02, 01:35 authored by Jaehoon Chung, Hiroyuki Kubota, Yu-ichi Ozaki, Shinsuke Uda, Shinya Kuroda

We selected genes whose expression level showed a greater than 4-fold change over the control in response to each pattern of stimulation, such as transient NGF (T.NGF), PACAP (T.PACAP) and insulin (T.Insulin) stimulation, sustained NGF stimulation (S.NGF) and transient NGF stimulation with U0126 (U0126) or LY294002 (LY294002). Then, we selected genes commonly found to be responsive to transient NGF, transient PACAP, sustained NGF and transient NGF with LY294002, but unresponsive to transient insulin stimulation and transient NGF stimulation with U0126.

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