Generalized partial lymphocyte activation is dependent on an IFN-I response.

<p>Splenocytes from IFN-IR<sup>−/−</sup>, IFN-IIR<sup>−/−</sup>, IFN-I&IIR<sup>−/−</sup> and wild-type 129 mice were analysed for CD69 expression on CD3<sup>+</sup> cells 24h following <i>in vivo</i> immunization. Dot plots shows fluorescence profiles from mock, live A/PR8 infected and γ-A/PR8 immunized mice.</p>