Gene expression profile of PDGF-BB encapsulated microspheres in NFS vs. vehicle encapsulated microspheres in NFS. List of genes with greater than 10-fold change in expression from cDNArray analysis used as screening for subsequent qPCR analysis.

<p>Specimens harvested 7 days following treatment comparing the 25 µg PDGF-encapsulated in slow release PLGA microsphere group as compared to scaffold-only group are shown below.</p>