GAD-7, PHQ-9, PSQ-20 and EDI-2 scores and plasma NUCB2/nesfatin-1 levels in anorexic patients.

Patients with high anxiety displayed significantly higher NUCB2/nesfatin-1 levels compared to those with low anxiety (A). This resulted in a positive correlation of NUCB2/nesfatin-1 with anxiety in the whole anorexic patient sample (B), whereas depression scores (C), perceived stress scores (D) and eating disorder symptoms (E) did not correlate with plasma NUCB2/nesfatin-1. Differences between groups were calculated using t-tests. Data are expressed as mean ± standard deviation. * p < 0.05. Distribution of the data was determined by Kolmogorov-Smirnov test. Correlations were determined by Pearson’s or Spearman’s analyses depending on the distribution of the data. Values for r and p are indicated in the graph. Abbreviations: EDI-2, eating disorder inventory; GAD-7, general anxiety disorder questionnaire; NUCB2, nucleobindin2; PHQ-9, patient health questionnaire depression; PSQ-20, perceived stress questionnaire.