Figure_4.tif (459.34 kB)
Flt3L/Rapa therapy favors anergic induction in alloreactive T cells.
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posted on 2013-02-19, 22:20 authored by Ali Xiong, Lihua Duan, Jie Chen, Zhigang Fan, Fang Zheng, Zheng Tan, Feili Gong, Min Fang(A) Splenic T cells originated from cardiac allograft recipient mice at the time of rejection or at study endpoint (POD 100) were used as responder cells for MLR assay with donor-derived DCs (DC: T ratio of 1∶5). Bar graph was the summary of proliferation index (PI) of T cells isolated from different recipients. (B) The culture supernatants were harvested and cytokine IL-10 levels were quantification by ELISA. The data shown are representative of three independent experiments (*P<0.05).