Fall in circulating platelets induced by the i.v. injection of collagen and phenylephrine.

<p>Blood was collected from the yugular vein of isofluorane-anesthetized mice followed by i.v. injection of 150 ng collagen type I plus 15 ng of epinephrine per g of mice body weight, as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026025#s2" target="_blank">Methods</a>. At the indicated time blood was withdrawn from the contralateral yugular vein and the number of platelets determined. Seven animals were analyzed in each group. The values are means ±SEM. By t-test * p<0.05.</p>