Figure_4.tif (1.39 MB)
FOXO1 Binds to −125/−91 of the Fshb Promoter.
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posted on 2014-11-25, 02:43 authored by Chung Hyun Park, Danalea V. Skarra, Alissa J. Rivera, David J. Arriola, Varykina G. ThackrayTnT Flag-FOXO1-CA was incubated with a consensus FBE, −305/−271, −275/−241, −245/−211, −215/−181, −185/−151, −155/−121, or −125/−91 Fshb probes and tested for complex formation in EMSA. FOXO1-CA-DNA complex on the FBE is shown in lane 1, IgG control in lane 2 and Flag supershift is shown in lane 3. The FOXO1-CA-DNA complex (arrow) and antibody supershift (ss) are indicated on the left and right of the gel.
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activin inductionFOXO 1FOXO 1 Diminishes Activin InductionFOXO 1 suppressionFOXLL βT cellsFOXO 1 decreases activin inductionFOXO 1 bindingsmadactivin response elementsFOXO 1 transcription factor modulates activinFOXO 1 DNA bindingFOXO 1 interactionFshb promoteractivin induction mapsdbdmurine Fshb gene expression
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