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Expression of Insulin Like Growth Factors, Receptors, and Binding Proteins with Embryonic Stem Cell Differentiation.
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posted on 2012-02-21, 02:27 authored by Stephanie M. Piecewicz, Ambarish Pandey, Bhaskar Roy, Soh Hua Xiang, Bruce R. Zetter, Shiladitya SenguptaA) mRNA levels of IGFR-1, IGFR-2, IGF1, and IGF2 increase with time in differentiating embryoid bodies measured from days 1–7, although IGF1 appears to remain steady, pointing to its role in both pluripotency and differentiation. * denotes P<0.05 to day 1 control, Rn denotes normalized reporter.