Experimental setup of mixed infection of experiments 1 and 2.

<p>Infections were initiated with a mixture of resistant and susceptible parasites with the specified R∶S ratio inoculum on day 0 (Experiment 1) or with 10<sup>6</sup> susceptible parasites on day 0 and ∼25 resistant parasites on day 5 (Experiment 2). Number of mice at the start of the experiment is given, with the number used in the analysis (after exclusion based on infection establishment and mortality; see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003578#s4" target="_blank">Materials and Methods</a> for details) in brackets.</p>