Evaluation of combination agents in CD-DST.

The in vitro sensitivity was expressed as the T/C ratio, in which T is the total volume of living cancer cells in the treated group, and C is the total volume of living cancer cells in the control group. Positive, T/C <60%; negative, T/C ≥ 60%.

5-FU, 5-fluorouracil; SN38, the active metabolite of irinotecan; OHP, the active metabolite of oxaliplatin.

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statistically significant.

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