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Engineering D-Amino Acid Containing Collagen Like Peptide at the Cleavage Site of Clostridium histolyticum - Fig 5 Collagenase for Its Inhibition

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posted on 2015-05-14, 02:57 authored by Punitha Velmurugan, Raghava Rao Jonnalagadda, Balachandran Unni Nair

(a) Change of CD spectral signature of DAla substituted peptide with increase in time from 0 to 120 min at 37°C in 2D-view; (b) Change of CD spectral signature of DAla substituted peptide upon interaction with bacterial collagenase with increase in time from 0 to 120 min at 37°C in 2D-view (c) Relative amount of different structural elements in DAla substituted collagen like peptide with increase in time from 0 to 120 min at 37°C using CD data by CONTIN software package; (f) Relative amount of different structural elements in DAla substituted collagen like peptide upon interaction with bacterial collagenase with increase in time from 0 to 120 min at 37°C using CD data by CONTIN software package.

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