Effects of replenishment of IL-13 in DSS-induced colitis.
IL-13−/− mice were treated with rmIL-13 (2 µg/day) injections or vehicle. rmIL-13 treatment started 3 days prior to 5 days of 5% DSS treatment. All groups received 5% DSS in the drinking water to induce colitis. (A) Number of 5-HT expressing EC cells per 10 glands and (B) colonic 5-HT content. (i) and (ii) Representative micrograph and arrows indicate 5-HT expressing EC cells. *Represents statistical significance where p<0.05.