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Effects of PDGF and VEGF receptor kinase inhibitors on tumor vascularization.
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posted on 2009-12-04, 00:57 authored by Agnieszka Kłosowska-Wardęga, Yoko Hasumi, Mikhail Burmakin, Aive Åhgren, Linda Stuhr, Ingrid Moen, Rolf K. Reed, Kristofer Rubin, Carina Hellberg, Carl-Henrik HeldinSections of KAT-4 tumors from mice treated with vehicle, STI571 or PTK/ZK, alone or in combination were stained for endothelial cells of blood vessels by CD31 antibodies and then subjected to stereological analysis. Data are presented as means +/− SEM. Asterisks indicate statistically significant differences (p<0.05) compared to control (vehicle treatment).
