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Effects of IL-13 deficiency in DSS-induced colitis.

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posted on 2013-08-28, 01:31 authored by Md. Sharif Shajib, Huaqing Wang, Janice J. Kim, Ivana Sunjic, Jean-Eric Ghia, Emmanuel Denou, Matthew Collins, Judah A. Denburg, Waliul I. Khan

WT and IL-13−/− mice were given 5% DSS in drinking water to induce colitis. (A) Number of 5-HT expressing EC cells per 10 glands and colonic sections immunostained for 5-HT expressing EC cells after 5 days of DSS administration in WT and IL-13−/− mice. (B) Colonic 5-HT amount. (i) and (ii) Representative micrograph and arrows indicate 5-HT expressing EC cells. *Represents statistical significance where p<0.05.

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