Effects of IGF and chemerin on Ca<sup>2+</sup> signalling in MSCs.

<p><i>A</i>. Images of Fluo-4 loaded MSCs taken in the absence (left) and the presence (right) of chemerin (100nM), respectively. <i>B</i>. IGF-II (100 ng.ml<sup>-1</sup>, top) and chemerin (100nM, Ch) induce Ca<sup>2+</sup> oscillations in Fluo-4 loaded cells. <i>C</i>. Relaxation of Ca<sup>2+</sup> transients induced by chemerin or IGF-II after removal of external Ca<sup>2+</sup> (Ca<sup>2+</sup> free solution with 2mM EGTA).</p>