Effect of acute per os DON administration on meal microstructure.

A: Graph showing meal size over 24 h after an oral gavage of either water (vehicle, black histograms) or DON (12.5 mg/kg, red histograms) in an adult mouse. Note that the width of each bar represents the meal duration. Time is indicated in zeitgeber time, 12 being the transition between lights on and lights off and 0 or 24 the transition between lights off and lights on. The dark period is represented by the shaded box. B: Meal microstructure analysis performed during the dark period for mice that received either water (white bars) or DON (12.5 mg/kg, orange bars). *P<0.05 and **P<0.01, significantly different from vehicle-treated mice.