Effect of IL-18 on induction of Th2 differentiation.
(A) Effect of IL-18 on IL-4 secreting splenocytes ELISPOTS. (B) T cell differentiation protocol used in Panels 3C–E and Fig. 4. (C, D and E) Effect of IL-18 or IL-4 on Th2 differentiation of naïve CD4+ T-cells isolated from WT mice (C), IL-4−/− mice (D) and WT and STAT6−/− mice (E). n = 5−7 per group.