Figure_9.tif (244.51 kB)
Effect of AMD3100 treatment on CXC chemokine receptor 4+ (CXCR4+) cells.
figure
posted on 2014-02-24, 03:32 authored by Daniela Farkas, Donatas Kraskauskas, Jennifer I. Drake, Aysar A. Alhussaini, Vita Kraskauskiene, Harm J. Bogaard, Carlyne D. Cool, Norbert F. Voelkel, Laszlo FarkasQuantification of the number of total CXCR4+ cells (A), CXCR4+ von Willebrand Factor+ (vWF+) cells (B) and CXCR4+ α-smooth muscle actin+ (α-SMA+) cells (C) per vessel in pulmonary arteries of SuHx animals treated with vehicle or AMD3100. The data indicate that while the number of total CXCR4+ cells and CXCR4+ α-SMA+ cells per vessel was significantly reduced by AMD3100 treatment, there was only a small trend towards decreased number of CXCR4+ vWF+ cells per vessel in AMD3100 treated SuHx animals. n = 4 animals/group. * P<0.05, *** P<0.0001.
