Figure_7.tif (2.62 MB)
EM analysis of 293T cells transfected with WT pNL4-3 or the indicated mutant derivatives and treated without (no inhibitor) or with 5 µM PF-46396.
figure
posted on 2012-11-08, 01:52 authored by Kayoko Waki, Stewart R. Durell, Ferri Soheilian, Kunio Nagashima, Scott L. Butler, Eric O. FreedNote highly defective EM morphology and accumulation of Gag at the plasma membrane for the mutants in the absence of PF-46396, and the rescue of assembly/release in the presence of compound. Scale bars: a–d, f–h, j–p = 100 nm; e, i = 500 nm.