Dot plots of three HSV-2 gene expression levels in SAID affected probands, unaffected twins, and matched, unrelated healthy controls.

<p>The individual normalized signal data for <i>UL19</i> (A, probe 1 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0142486#pone.0142486.t003" target="_blank">Table 3</a>), <i>UL36</i> (B) and <i>RS1</i> (C) were plotted according to the three study groups: probands, unaffected twins, and matched, unrelated healthy controls. Statistically significant <i>p</i> values between any two groups are shown (*) and were calculated using one-way ANOVA with corrections for multiple comparisons. The proposed “normal range” values were derived from the mean plus three standard deviations (SD, dash line) of healthy control expression values.</p>