Dose-dependence of GATA6 expression level induced by S1P (A) and role of the transcription factors GATA6, LMCD1 (B,C) on the expression levels of SM markers induced by S1P in mesoangioblasts.

<p>Mutual regulation of the transcription factors GATA6, LMCD1 and TRPS1 (D,E,F). Real time PCR analysis of GATA6 (A) was performed in cells challenged with the indicated concentrations of S1P for 6 h. Real-Time PCR analysis of CNN1 (B), TPM1 (C), GATA6 (D), LMCD1 (E), TRPS1 (F) was performed in cells transfected with scrambled-, GATA6- or LMCD1-siRNA and stimulated with S1P for 24 h.</p>