Dopamine bioavailability and correlation to locomotor activity generation.

Total DA in striatum ((str) a, c, e) versus substantia nigra ((SN) b, d, f) and correlation to mean lifetime locomotor activity measures in all 14 subjects, ages 12 and 30 months (n = 7 each age group). The following are the Spearman correlation values and p-values; Movement number, a. str, p = 0.65, r = 0.13 b. SN, **p = 0.008, r = 0.68, Horizontal activity, c. str, p = 0.58, r = 0.16 d. SN, **p = 0.008, r = 0.72; Time spent moving, e. str, p = 0.42, r = 0.24 e. SN, *p = 0.01, r = 0.64. Additional statistical correlations are presented in Table 1.