Fig_4.tif (3.15 MB)
Display of results at the individual diagnosis level for the disease category “ILD-related to the alveolar surfactant region”.
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posted on 2015-02-18, 03:28 authored by Matthias Griese, Hannah G. Kirmeier, Gerhard Liebisch, Daniela Rauch, Ferdinand Stückler, Gerd Schmitz, Ralf ZarbockLipid class composition (graph A) on left side) and phosphatidylcholine species composition (graph B) on right side) are indicated as means for each diagnosis. The number of subjects is detailed in Table 1. The numbers above the columns indicate the mean phospholipid concentrations (μmol/l). No statistical comparisons were done; the graphical display should allow a rapid identification of deviations from the controls. The other species are provided in S4 Fig. Only lipid species present at an abundance of > 0.5% are displayed.
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lung vesselsalveolar surfactant32 carbonssurfactant lipid metabolism.ConclusionsLipidomicalveolar surfactant regionreactive lymphoid lesionsreference populations115 childrenHealthy Childrenphosphatidylglycerol speciessurfactant alterationslung diseaseselectrospray ionization tandem mass spectrometrydisease categorization.MethodsComprehensive lipidomics profilesABCA 3monounsaturated phosphatidylcholine speciesdistress syndromeChildhood Interstitial Lung Disease BackgroundLipids accountpart ILDSurfactant Lipidomicsgrowth abnormalitiesspecies compositionspecies patternalveolar disorders lipidomic profiles
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