Differential gene expression in the midbrain of human cocaine abusers

. Transcript abundances were quantified in specimens from cocaine abusers and control subjects. All subjects died of gunshot wounds (see Table 1 as well as Materials and Methods for case characteristics). Data from cocaine abusers are expressed as a percentage (mean + SEM) of control subjects. * p<0.05; ** p<0.005 by 1-tailed t-test for independent means. Abbreviations: ACTB, actin; TH, tyrosine hydroxylase; DAT, dopamine transporter; FOXA2, forkhead box A2; H3F3B, histone variant H3, family 3B; NFKBIA, nuclear factor kappa B inhibitor alpha; GADD45B, growth arrest and DNA damage-inducible beta; CCL2, chemokine C-C motif ligand 2; JUN, jun proto-oncogene.