Diarrhea and virus shedding in gnotobiotic piglets after oral inoculation with VirWa HRV (P[8]G1).

Abbreviations: n = number of animals per group; AUC: area under the curve.

Determined by ELISA and CCIF.

Diarrhea duration was defined as the number of days with fecal score ≥2. Stool consistency was scored daily (0 = normal; 1 = pasty; 2 = semi-liquid; 3 = liquid).

Mean severity: mean cumulative scores from 0 to 21 PID (sum daily fecal score)/n. Proportions or means in the same column with different superscript upper case letters differs significantly (Fisheŕs exact test, p<0.05 and Kruskall-Wallis rank sum test; p<0.05). Piglets were fed with 210 ml of sterile milk, twice a day, for 9 days with or without the addition of the corresponding volume of Wa HRV IgY pools, VP6 IgY pool, control IgY pool or Wa HRV porcine IgG pool, according to the experimental group.