Delayed toxicity of rats following LeTx challenge with RDI-IgG1 and RDI-IgG2 fusion proteins.

<p>Male 200 gram HSD rats (5/group) were co-injected i.v. with LeTx (40 µg PA+12 µg LF) and either 19 µg of RDI; or 49 µg of either RDI-eIgG1, RDI-IgG1, or RDI-IgG2. Rats were monitored and time of death recorded.</p>