Figure_4.tif (148.34 kB)
Contribution of S100A8/A9 to cytokine and chemokine production during UTI.
figure
posted on 2013-02-20, 22:56 authored by Mark C. Dessing, Loes M. Butter, Gwendoline J. Teske, Nike Claessen, Chris M. van der Loos, Thomas Vogl, Johannes Roth, Tom van der Poll, Sandrine Florquin, Jaklien C. LeemansChemokine and cytokine levels (KC, MIP-2 and TNF-α) in bladder (figure 4A–C) and kidney (figure 4D–F) homogenates from WT mice (black squares) and S100A9 KO mice (white squares), 24 and 48 hours after inoculation with 4.5×108 or 9.0×108 CFU E. coli/mouse. Sham mice were sacrificed 24 hours after inoculation with sterile PBS. Single experimental data are mean ± SEM. N = 6–9 mice per group, *P<0.05 vs. WT mice.
