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File S1 - Consumption of Dairy Products and Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

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posted on 2013-09-02, 02:24 authored by Neil Murphy, Teresa Norat, Pietro Ferrari, Mazda Jenab, Bas Bueno-de-Mesquita, Guri Skeie, Anja Olsen, Anne Tjønneland, Christina C. Dahm, Kim Overvad, Marie Christine Boutron-Ruault, Françoise Clavel-Chapelon, Laura Nailler, Rudolf Kaaks, Birgit Teucher, Heiner Boeing, Manuela M. Bergmann, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Valeria Pala, Rosario Tumino, Paolo Vineis, Salvatore Panico, Petra H. M. Peeters, Vincent K. Dik, Elisabete Weiderpass, Eiliv Lund, Jose Ramon Quiros Garcia, Raul Zamora-Ros, Maria José Sánchez Pérez, Miren Dorronsoro, Carmen Navarro, Eva Ardanaz, Jonas Manjer, Martin Almquist, Ingegerd Johansson, Richard Palmqvist, Kay-Tee Khaw, Nick Wareham, Timothy J. Key, Francesca L. Crowe, Veronika Fedirko, Marc J. Gunter, Elio Riboli

Supporting information. Figure S1. Multivariable hazard ratios and 95% confidence intervals of colorectal cancer risk by country, per 400 g/day increase in total dairy intake. Hazard ratios estimated by Cox proportional hazards models adjusting for total energy intake (continuous), body mass index (continuous), physical activity index (inactive, moderately inactive, moderately active, active, or missing), smoking status and intensity (never; current, 1–15 cigarettes per day; current, 16–25 cigarettes per day; current, 16+ cigarettes per day; former, quit ≤10 years; former, quit 11–20 years; former, quit 20+ years; current, pipe/cigar/occasional; current/former, missing; unknown), education status (none, primary school completed, technical/professional school, secondary school, longer education including university, or not specified), ever use of contraceptive pill (yes, no, or unknown), ever use of menopausal hormone therapy (yes, no, or unknown), menopausal status (premenopausal, postmenopausal, perimenopausal/unknown menopausal status, or surgical postmenopausal), alcohol consumption (yes or no; and continuous) and intakes of red and processed meat and fibre (both continuous), and stratified by age (1-year categories), sex, and centre. Figure S2. Multivariable hazard ratios and 95% confidence intervals of colorectal cancer risk by country, per 200 mg/day increase in total dietary calcium (B). Hazard ratios estimated by Cox proportional hazards models adjusting for total energy intake (continuous), body mass index (continuous), physical activity index (inactive, moderately inactive, moderately active, active, or missing), smoking status and intensity (never; current, 1–15 cigarettes per day; current, 16–25 cigarettes per day; current, 16+ cigarettes per day; former, quit ≤10 years; former, quit 11–20 years; former, quit 20+ years; current, pipe/cigar/occasional; current/former, missing; unknown), education status (none, primary school completed, technical/professional school, secondary school, longer education including university, or not specified), ever use of contraceptive pill (yes, no, or unknown), ever use of menopausal hormone therapy (yes, no, or unknown), menopausal status (premenopausal, postmenopausal, perimenopausal/unknown menopausal status, or surgical postmenopausal), alcohol consumption (yes or no; and continuous) and intakes of red and processed meat and fibre (both continuous), and stratified by age (1-year categories), sex, and centre. Table S1. Multivariable hazard ratios (95% confidence intervals) of colorectal cancer risk in men by dairy product consumption categories. Table S2. Multivariable hazard ratios (95% confidence intervals) of colorectal cancer risk in women by dairy product consumption categories. Table S3. Multivariable hazard ratios (95% confidence intervals) of colorectal cancer risk in men by dietary calcium intake categories. Table S4. Multivariable hazard ratios (95% confidence intervals) of colorectal cancer risk in women by dietary calcium intake categories.

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