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Congenicity across multiple generations of backcrossing R6/2 mice to C57BL/6J.

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posted on 2013-02-20, 11:03 authored by Randi-Michelle Cowin, Nghiem Bui, Deanna Graham, Jennie R. Green, Stephan Grueninger, Lisa A. Yuva-Paylor, Arsalan U. Syed, Andreas Weiss, Richard Paylor

Average percentage of homozygous B6 markers based on the 96-marker panel. Average percent B6 homozygosity was less than 50% after the first backcross but reached congenicity of 95% by the N4 generation.

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