Competition experiments between susceptible and resistant strains, streptomycin and tetracycline.

<p>Competition experiments at different concentrations of antibiotics (A (<i>rpsL105 (K42R)</i>) and C (<i>Tn</i>10<i>d</i>tet), and calculated selection coefficients as a function of antibiotic concentrations (B and D). Fig. A and C are each based on one single competition experiment (averages of four competitions), while Fig. B and D are calculated from the selection coefficients of up to 20 competitions (Table S3 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002158#ppat.1002158.s003" target="_blank">Text S1</a>). Standard errors of the mean are indicated.</p>