Competition experiments between susceptible and resistant strains, streptomycin and tetracycline.

Competition experiments at different concentrations of antibiotics (A (rpsL105 (K42R)) and C (Tn10dtet), and calculated selection coefficients as a function of antibiotic concentrations (B and D). Fig. A and C are each based on one single competition experiment (averages of four competitions), while Fig. B and D are calculated from the selection coefficients of up to 20 competitions (Table S3 in Text S1). Standard errors of the mean are indicated.