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Comparison of three treatments at 45dpi by using predicted model values.

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posted on 2013-02-20, 13:54 authored by Aleksandar Denic, Slobodan I. Macura, Arthur E. Warrington, Istvan Pirko, Brandon R. Grossardt, Larry R. Pease, Moses Rodriguez

Statistical analysis was performed for each day before and after the treatment. A, C) Horizontal nocturnal activity of rHIgM12-treated mice as compared to control IgM- and saline-treated mice significantly diverged on day 13 (p = 0.015) and day 9 (p = 0.036) post-treatment, respectively. B, D) Vertical (rearing) activity of rHIgM12-treated mice diverged/improved on day 14 (p = 0.019) and day 6 (p = 0.037) post-treatment, respectively. E, F) Comparisons of control IgM- vs. saline-treated mice did not reveal major biological changes neither for horizontal (E) nor for vertical (F) activity. Black arrows denote days with onset of significant improvement. The pointwise 95% confidence bands are given for each day.

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