Figure_1.tif (137.03 kB)
Comparison of the cytokine kinetics of HIV-specific mRNA and protein induction.
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posted on 2013-02-20, 23:01 authored by Duncan Chege, Yijie Chai, Sanja Huibner, Lyle McKinnon, Charles Wachihi, Makubo Kimani, Walter Jaoko, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Rupert Kaul, Anuradha Rebbapragada1×106 peripheral blood mononuclear cell samples from 4 HIV infected individuals were incubated with HIV CD8+ T cell HIV optimized epitope antigen e (HIV epitope pool) and mRNA and protein induction assayed via qPCR and CBA respectively. Bars represent median values with lines showing interquartile ranges measuring HIV-specific IFNγ (a), TNFα (b) and IL-2 (c) mRNA and protein induction kinetics are shown. Background levels of protein have been subtracted from reported values above.