Comparison of peak MuRF1-hiLUCs induction in different anatomical regions in response to different atrophic stimuli.

Levels of MuRF1-hiLUCs reporter induction were quantified in four or five muscle groups, depending on the view, from all three of the atrophy models investigated, throughout the time course of the studies (n = 8 for denervation and HLU, n = 10 for dexamethasone treatment). Graph bars correspond to day of peak reporter induction. Dotted lines represent 2.5 fold induction in luminescence. Differences in the level of MuRF1-hiLUCs reporter induction between muscle groups were analyzed using ordinary one-way ANOVA with Tukey's multiple comparisons test. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001. Data are presented as means (symbols) + SEM (lines).